This Voice Expeditions interview, conducted by Dr. Dugan Maddux for the Oral History of Nephrology, features Dr. Edmund Lowrie reflecting on his career at the forefront of dialysis innovation. From his early training in the 1960s—when dialysis was still an emerging therapy—to his later leadership in advancing dialysis care and outcomes, Dr. Lowrie shares a firsthand account of the people, ideas, and breakthroughs that shaped modern nephrology.