Nancy Sharp is a respected pioneer in nephrology nursing whose career paralleled the evolution of modern dialysis and kidney care. Beginning in the early days of chronic dialysis at Passavant Hospital in Chicago and later at Georgetown University Hospital, she helped care for some of the first long-term dialysis patients while witnessing firsthand the development of new technologies, vascular access methods, and transplant programs. Beyond her clinical work, she became a national leader in nursing advocacy, helping to build the legislative presence of the American Nephrology Nurses Association (ANNA) and championing the role of nurses in healthcare policy. In this interview, Nancy reflects on her experiences as a clinician, educator, advocate, and leader, offering a unique perspective on the history of nephrology and the vital contributions of nurses to the field.